Indee Labs is Simulating Its Way to Scalable Gene-modified Cell Therapy

Gene-modified cell therapy (GMCT) represents the most effective platform for many patients with advanced disease. These therapies, however, are held back by inefficient development processes and manufacturing scales that are limited to a minute fraction of the relevant patient populations due to current gene delivery methods such as viral vectors. Simulation is helping to accelerate this development process and advance cell therapy.

Indee Labs is a Y Combinator company spun out of the Australian National Fabrication Facility. The team is developing novel gene delivery technology that uses ANSYS computational fluid dynamics solutions to gently and efficiently deliver genetic materials such as CRISPR to your immune cells. Indee Labs views gene delivery as the most problematic step in developing and manufacturing GMCTs since a global shortage in viral vectors has led Big Pharma to invest hundreds of millions of dollars into their own manufacturing facilities. Continue reading

7 Examples of Engineering Simulation Excellence Added to the ANSYS Hall of Fame

It always astounds me what our ANSYS customers accomplish with our software. Applying Pervasive Engineering Simulation, engineers, designers and students from organizations around the world and across a vast array of industries submitted a large number of innovative entries to be considered for the ANSYS Hall of Fame. It was very difficult for our judges to pick the winners among such great examples of engineering excellence.

Here are the winners of the 2018 ANSYS Hall of Fame Competition.

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Cloud Computing Speeds Antenna Design

In a previous blog, I noted that born in the cloud companies can be a boon to tech startups looking to optimize precious resources. In this post, I offer a spectacular case in point.

Optisys had big goals and big compute needs. Designing its next-gen antenna, the Utah-based startup sought order-of-magnitude reductions in size, weight and lead time, and a cost-effective solution for running large, concurrent RF electronics simulations. Establishing an in-house IT function wasn’t an option: Optisys (like many startups) had little appetite or budget for investing outside its core business. Instead, it adopted Rescale’s cloud-based platform to satisfy its simulation needs. Continue reading

ANSYS Discovery Live Engineering Design Competition

Over the last four months, I’ve had the pleasure of talking with several ANSYS Discovery Live technology preview users and learning about their unique stories. Regardless of the user, there is one common theme I hear — excitement. Users are excited about many things this technological breakthrough brings to them, and I am happy to announce another exciting aspect of Discovery Live.

Introducing the 1st Discovery Live Engineering Design Competition

Starting today, we are launching a Discovery Live engineering design competition! This is an opportunity for anyone to put on display their experience with Discovery Live, show the world their findings, and win awesome prizes. Continue reading

ANSYS and Green Hills Software Together at CES 2018

Safety first — especially when it comes to engineering control systems for autonomous vehicles. These systems must meet the same high-level safety standards long-mandated for aerospace and defense technologies. In addition, the operating systems that run the certified programs must also be safe — from hackers.

Together, ANSYS and Green Hills Software have developed a comprehensive solution for driverless cars that rises to the level of ISO 26262 (ASIL D) certification and is invulnerable to hacker attacks. Continue reading

Looking Forward to AIAA SciTech Forum

In a few days, I’ll be in Florida at the AIAA SciTech Forum, along with some of our technology experts. This is the place where you can get an inside look at how much innovation is going on in the aerospace industry today. At ANSYS, we are constantly expanding our simulation platform capabilities through internal development and integration, acquisitions and partnership. Let me highlight just a tiny part of what happened in 2017 and what you can “touch” at our booth at SciTech.

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Investigating Placement of Antennas Inside an Aircraft Fuselage

You may be surprised to learn that a standard passenger jet can have 30 to 50 antennas protruding from the aircraft’s external surface, producing drag forces that can drastically reduce fuel efficiency at a time when airlines are trying to reduce energy consumption. Most antenna designs are engineered for safety purposes, such as air traffic control, traffic collision avoidance, instrument landing systems and distance measuring equipment. Increasingly, antennas are being added to meet passenger demand for more and faster Wi-Fi access, in-flight TV and cellphone applications.

aircraft antennas

Antennas are mounted on the exterior of today’s airliners

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The Firenze Race Team (FRT) Engineers Innovation

As students at the University of Florence, we aren’t just racing to class, we’re racing around Europe. Last season was particularly exciting for our 35-member Firenze Race Team (FRT). We designed two new single-seater cars — the FR-17T and FR-17DT — and introduced them at Formula Student competitions in Italy and Germany.

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Startups Bring Excitement to Established Industries

Startup companies are using ANSYS software in exciting and groundbreaking ways. It should come as no surprise then that some of my favorite articles in our ANSYS magazines (ANSYS Advantage and Dimensions) in 2017 were generated with the assistance of startups. I think the enthusiasm of these hardworking teams of entrepreneurs who participate in the ANSYS Startup Program is demonstrated in these articles about how their pioneering products are being developed.

Many startups literally begin in a garage. For example, Kyle Doerksen, Founder and CEO of Future Motion, inventor of the Onewheel motorized skateboard, prototyped his idea in his garage before launching a Kickstarter campaign. With the help of engineering simulation his team quickly moved from prototype to mass production. Future Motion has shipped more than 10,000 products, expediting many short commutes and creating a new form of transportation and recreation along the way.

startup develps onewheel Continue reading

Ensuring Signal Integrity Throughout a Channel

Electronic devices — with well-designed signal integrity (SI) — have transformed the way we communicate, work, learn and entertain. Around the globe, we find smart phones, fiber-optic and wireless networks, pocket-size computers, LED screen displays that mimic paper and unmanned aerial vehicles (UAVs) that deliver packages. Automobiles are filled with electronics that control engine functions, keep wheels from skidding, avoid accidents, direct our travel routes and, now, drive themselves. Aircraft are equipped with radar, fly-by-wire systems and airborne communications. And the innovations keep coming…

deep channel analysis for signal integrity

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