Gene-modified cell therapy (GMCT) represents the most effective platform for many patients with advanced disease. These therapies, however, are held back by inefficient development processes and manufacturing scales that are limited to a minute fraction of the relevant patient populations due to current gene delivery methods such as viral vectors. Simulation is helping to accelerate this development process and advance cell therapy.
Indee Labs is a Y Combinator company spun out of the Australian National Fabrication Facility. The team is developing novel gene delivery technology that uses ANSYS computational fluid dynamics solutions to gently and efficiently deliver genetic materials such as CRISPR to your immune cells. Indee Labs views gene delivery as the most problematic step in developing and manufacturing GMCTs since a global shortage in viral vectors has led Big Pharma to invest hundreds of millions of dollars into their own manufacturing facilities. Continue reading →
It always astounds me what our ANSYS customers accomplish with our software. Applying Pervasive Engineering Simulation, engineers, designers and students from organizations around the world and across a vast array of industries submitted a large number of innovative entries to be considered for the ANSYS Hall of Fame. It was very difficult for our judges to pick the winners among such great examples of engineering excellence.
As students at the University of Florence, we aren’t just racing to class, we’re racing around Europe. Last season was particularly exciting for our 35-member Firenze Race Team (FRT). We designed two new single-seater cars — the FR-17T and FR-17DT — and introduced them at Formula Student competitions in Italy and Germany.
Startup companies are using ANSYS software in exciting and groundbreaking ways. It should come as no surprise then that some of my favorite articles in our ANSYS magazines (ANSYS Advantage and Dimensions) in 2017 were generated with the assistance of startups. I think the enthusiasm of these hardworking teams of entrepreneurs who participate in the ANSYS Startup Program is demonstrated in these articles about how their pioneering products are being developed.
Many startups literally begin in a garage. For example, Kyle Doerksen, Founder and CEO of Future Motion, inventor of the Onewheel motorized skateboard, prototyped his idea in his garage before launching a Kickstarter campaign. With the help of engineering simulation his team quickly moved from prototype to mass production. Future Motion has shipped more than 10,000 products, expediting many short commutes and creating a new form of transportation and recreation along the way.
Multihull ships create engineering challenges that are “out of range” of conventional ship design techniques. They require complex, CFD analysis to optimize multiple performance variables like resistance, endurance, stability, seakeeping, etc. In this article, we take you behind the scenes at KUASAR MARIN Engineering Inc., where we leveraged ANSYS Fluent to explore design iterations for a three-hulled, high-speed passenger ferry that could compete with existing two-hull catamarans.
The Laboratory for Environmental Flow Modeling at the University of California, Riverside, has used ANSYS Fluent software to model a variety of environmental flows. As a third year Ph.D. candidate student in Mechanical Engineering, I recently evaluated the influence of roadside vegetation barriers on the near-road air quality using Computational Fluid Dynamics (CFD), as part of a research team that included my colleague Seyedmorteza Amini and my advisor Dr. Marko Princevac.
Exposure to traffic-related air pollution leads to public health concerns such as respiratory problems, birth and developmental defects, cardiovascular effects and cancer for people who live and work near major roadways. The near-road air quality can be improved directly by deploying vehicle emission control techniques, using alternative fuels or electric vehicles (EVs), or via passive pollutant control and roadside configuration design such as solid and vegetative barriers. Continue reading →
“Please fasten your seat belts, we may encounter some turbulence as we enter the clouds ahead,” the pilot announced on my flight back from a big computer conference in Denver last month. The lady sitting next to me leaned over and admitted: “I never really understand what the pilot means by that announcement.” It reminded me that you may also need some clarity about cloud computing for your ANSYS simulations.
Bumps along a cloud-computing journey can be caused by concerns about security and where the data is stored, lack of licensing options and/or end-user productivity. We have taken steps to ensure you can move in and out of the cloud smoothly, and in analogy with what I just wrote: in our case “no seat belts required.”
Nature is full of amazing materials. Wood and bone, for example, are natural composites with finely-tuned microstructures. They have optimized fiber alignment for enhanced strength. At Fortify — an additive manufacturing startup — we wondered if harnessing the power of natural composites in 3-D printing could help us to create high-performance end-use parts.
Our observations of the natural world led to the development of our fluxprint technology, which utilizes magnetic fields in a 3-D printer to align carbon fibers throughout a printed composite part. This process results in high-performance components with high-geometric complexity and incredible strength-to-weight ratios. Continue reading →
2017 is winding down. Have you thought about making a career change? Why not start off 2018 with a new career at ANSYS?
ANSYS hires some of the best and brightest. Join us in developing software that touches almost every product in the market. Check out our careers site for other openings. We update our site daily so check back often.
We can only accept applications via our on-line site. I encourage you to apply today. Continue reading →